Techniques were developed to provide direct quantitation of apolipoprotein A-I (apoA-I) synthesis rates in rat small intestine.Following intralumenal administration of a pulse of [3H]leucine, newly synthesized enterocyte apoA-I was quantitated by specific immunoprecipitation and compared to [3H]leucine incorporation into total trichloroacetic acid-
Abstract Graph neural networks (GNNs) have emerged as powerful tools to accurately predict materials and molecular properties in computational and automated discovery pipelines.In this article, we exploit the invertible nature of these neural networks to directly generate molecular structures with desired electronic properties.Starting from a rando
Pruritus of chronic spontaneous urticaria (CSU) is one of the most common and irritating sensations that severely affects the quality of life.However, the changes in the functional connectivity (FC) between thalamic subregions and other brain regions have not been fully elucidated.This study aimed to explore the potential changes in brain neural ci
Organic molecules preserved in fossils provide a wealth of new information about ancient life.The discovery of almost unaltered complex organic molecules in well-preserved fossils raise the question of how common such occurrences are in the fossil record, how to differentiate between endogenous and exogenous sources for the organic matter and what